Population
Human peripheral blood leukocytes (12-58 separate batches)
Comparison
Exposure to four wild-type strains and two… vs Different virus strains
Design
Preclinical
Authors
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Animal data on strain-specific IFN induction; leaves open genetic and virus determinants of human leukocyte responses.
The capacity of human leukocytes to form interferon in vitro is determined by both the individual's genetic make-up and the specific virus.
Pitkäranta et al. (1991) studied this question.
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