Why the study?
Does isoflurane alter the contractile response to norepinephrine in isolated rat mesenteric resistance arteries?
Does isoflurane alter the contractile response to norepinephrine in isolated rat mesenteric resistance arteries?
Isoflurane modulates vascular tone through a dual mechanism involving endothelium-dependent enhancement via superoxide anions and endothelium-independent inhibition.
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Isoflurane's vascular effects in rat arteries should not alter clinical vasopressor use; hypothesis-generating for human translation.
Izumi et al. (2001) studied this question.
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