Why the study?
Does anti-CD40L/B7-1 mAb treatment reduce myocardial inflammation in a murine model of acute viral myocarditis?
Does anti-CD40L/B7-1 mAb treatment reduce myocardial inflammation in a murine model of acute viral myocarditis?
Inhibition of the CD40/CD40L costimulatory pathway reduces myocardial inflammation in a murine model of viral myocarditis, highlighting a potential immunotherapeutic target.
No takes yet. Share an insight, caveat, or question.
Should not yet change myocarditis management; hypothesis-generating for CD40/CD40L-targeted immunotherapy in humans.
Seko et al. (1998) studied this question.
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