Identified wildtype 1 poliovirus and enterovirus 109 as the cause of a large outbreak of acute flaccid paralysis in adults in Congo with an unusually high case fatality rate of 41.3%.
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Alerts clinicians to poliovirus in adult AFP; leaves open enterovirus 109 co-infection mechanisms and adult susceptibility.
An outbreak of flaccid paralysis syndrome in adults is ongoing in Congo. Molecular analysis of faecal, throat and cerebrospinal samples identified wildtype 1 poliovirus and an additional enterovirus C strain related to enterovirus 109 as the cause. As of 22 November, the cumulative number of cases was 409, of which 169 (41.3%) were fatal. This is one of the largest wild type 1 poliovirus outbreaks ever described associated with an unusually high case fatality rate.
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Grard et al. (2010) studied this question.
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