Anticoagulant therapy for pulmonary infarction can be complicated by severe and potentially fatal hemothorax.
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Warrants caution with anticoagulation for pulmonary infarction due to hemothorax risk; leaves open safer management strategies.
Two elderly women had hemothorax as a complication of anticoagulant therapy for pulmonary infarction. To our knowledge, this complication has not previously been reported. Both patients were treated with heparin sodium and warfarin sodium following pulmonary infarction. Excess anticoagulant effect developed in both, and both had significant intrapleural hemorrhage, which was fatal in one case. Clinical differentiation between simple pulmonary emboli and emboli with infarction is difficult but important.
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Harvey B Simon (1969) studied this question.
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