Why the study?
Current ICDs require high voltage and energy that can impair cardiac function and induce arrhythmias, creating demand for an ICD operating effectively at lower energy.
Does a specific configuration of sheet-shaped epicardial electrodes reduce the defibrillation threshold in a heart simulator?
Does a specific configuration of sheet-shaped epicardial electrodes reduce the defibrillation threshold in a heart simulator?
Computational modeling suggests that top-bottom sheet-shaped epicardial electrodes with optimal clearance and backside insulators can achieve low-energy defibrillation.
May enable lower-energy defibrillation; leaves open clinical safety and efficacy of sheet electrodes.
BACKGROUND: Current implantable cardioverter defibrillators (ICDs) require electric conduction with high voltage and high energy, which can impair cardiac function and induce another malignant arrhythmia. As a result, there has been a demand for an ICD that can effectively operate with lower energy to mitigate the risks of a strong electric shock. METHODS: A pair of sheet-shaped electrodes covering the heart were analyzed in three configurations (top-bottom, left-right, and front-back) using a heart simulator. We also varied the distance between the two electrodes (clearance) to identify the electrode shape with the lowest defibrillation threshold (DFT). We also investigated the ICD shock waveform, shock direction, and the effect of the backside insulator of the electrode. RESULTS: The DFT was high when the clearance was too small and the DFT was high even when the clearance was too large, suggesting that an optimal value clearance. The top-bottom electrodes with optimal clearance showed the lowest DFT when the biphasic shocks set the top electrode to a high potential first and then the bottom electrode was set to a high potential. An interval between a first shock waveform and a second shock waveform should be provided for low-energy defibrillation. Because the insulator prevents unnecessary current flow to the backside, the DFT of the electrodes with insulators is less than those without insulators. CONCLUSION: Painless defibrillation using sheet-shaped electrodes on the epicardium is predicated on the basis of results using a heart simulator.
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Okada et al. (2023) studied this question.
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