Why the study?
Do panic disorder patients have a heightened or deregulated autonomic nervous system at rest and during orthostatic challenge compared with healthy controls?
Population
40 participants (30 with panic disorder and 10 healthy controls)
Comparison
Orthostatic challenge (head-up tilt) vs Healthy controls
Design
Case-control
Authors
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Autonomic dysregulation in panic disorder may signal higher cardiac vulnerability; leaves open whether monitoring or intervention alters outcomes.
Do panic disorder patients have a heightened or deregulated autonomic nervous system at rest and during orthostatic challenge compared with healthy controls?
Panic disorder patients demonstrate deregulated autonomic arousal at rest and during orthostatic challenge, potentially indicating greater cardiac risk.
Martinez et al. (2010) studied this question.
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