Why the study?
Does high-dose loop diuretic use at discharge predict cardiovascular mortality in Japanese patients with heart failure?
Population
215 Japanese patients with decompensated heart failure admitted to a single hospital between March 2010 and…
Comparison
High-dose loop diuretics at discharge vs Low-dose loop diuretics at discharge
Design
Cohort
Follow-up
median 641 days
Authors
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High-dose loop diuretics at discharge were associated with higher CV mortality; hypothesis-generating and requires prospective confirmation before practice change.
Does high-dose loop diuretic use at discharge predict cardiovascular mortality in Japanese patients with heart failure?
Discharge on ≥40 mg/day of oral furosemide is strongly associated with increased cardiovascular mortality in Japanese patients with heart failure.
Okabe et al. (2017) studied this question.
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