Basal and Ischemia-Induced Transcardiac Troponin Release into the Coronary Circulation in Patients with Suspected Coronary Artery Disease

138 total patients: 105 consecutive stable patients with at least 1 coronary risk factor and suspected coronary artery disease (CAD) undergoing coronary angiography, and 33 patients without CAD undergoing an acetylcholine provocation test.

Measurement of highly sensitive cardiac troponin T levels in serum sampled from the peripheral vein, aortic root, and coronary sinus at baseline and after acetylcholine provocation.

Transcardiac troponin release (TTR), defined as the difference in troponin T levels between the coronary sinus and the aortic root.surrogate