May 26, 2012Clinical Chemistry
Cardiac Troponin T Measured by a High-Sensitivity Assay Predicts Recurrent Cardiovascular Events in Stable Coronary Heart Disease Patients with 8-Year Follow-up
Why the study?
Does high-sensitivity cardiac troponin T (hs-cTnT) predict recurrent cardiovascular events in patients with stable coronary heart disease?
Population
1050 stable coronary heart disease (CHD) patients, aged 30 to 70 years.
Comparison
Baseline plasma concentrations of… vs Lower quartiles of hs-cTnT concentrations
Design
Cohort
Follow-up
median 8.1 years
Authors
Discussion
Loading...
Member takes
Implication
hs-cTnT may refine risk stratification in stable CHD; leaves open need for prospective trials before clinical adoption.
Structured PICO
Does high-sensitivity cardiac troponin T (hs-cTnT) predict recurrent cardiovascular events in patients with stable coronary heart disease?
P
Population
1050 stable coronary heart disease (CHD) patients, aged 30 to 70 years.
I
Intervention
Baseline plasma concentrations of high-sensitivity cardiac troponin T (hs-cTnT)
C
Comparator
Lower quartiles of hs-cTnT concentrations
O
Outcome
Combined cardiovascular disease (CVD) end point (secondary CVD event)composite
Slightly increased hs-cTnT concentrations in stable CHD patients independently predict long-term recurrent cardiovascular events and improve risk reclassification.
Cite This Study
Köenig et al. (2012) studied this question.