Why the study?
Does sacubitril/valsartan improve clinical outcomes and reduce blood pressure in patients with heart failure and hypertension compared to ACEi and ARBs?
Population
Patients with heart failure and hypertension
Comparison
Sacubitril/valsartan vs Angiotensin-converting enzyme inhibitors and…
Design
Systematic_review
Authors
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May inform HF prescribing; leaves open need for updated RCTs in diverse populations.
Does sacubitril/valsartan improve clinical outcomes and reduce blood pressure in patients with heart failure and hypertension compared to ACEi and ARBs?
Sacubitril/valsartan provides superior cardiovascular benefits and blood pressure reduction compared to traditional ACEi and ARBs in patients with heart failure and hypertension.
Dargad et al. (2018) studied this question.
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