Why the study?
Does posture affect the venodilatory response to nitroglycerin in healthy volunteers?
Population
18 healthy young volunteers
Comparison
Nitroglycerin 0.8 mg spray administered in… vs Control conditions
Design
Other
Authors
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Posture modulates nitroglycerin venodilation in healthy volunteers; leaves open whether findings apply to patients or alter clinical use.
Does posture affect the venodilatory response to nitroglycerin in healthy volunteers?
Nitroglycerin causes a greater reduction in venous return to the heart when administered in the sitting position than in the supine position, as gravity compensates for an impaired venodilatory response.
Gascho et al. (1989) studied this question.
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