Why the study?
Does the rate and duration of glyceryl trinitrate delivery influence its haemodynamic effects on venous volume and blood pressure?
Population
19 subjects (n=7 for short IV infusion, n=7 for prolonged IV infusion, n=5 for sublingual tablet)
Comparison
Glyceryl trinitrate administered via short… vs Comparison between the three different…
Design
Other
Follow-up
Acute (minutes)
Authors
Loading...
May guide GTN dosing for targeted venous effects; leaves open clinical outcome impact.
Does the rate and duration of glyceryl trinitrate delivery influence its haemodynamic effects on venous volume and blood pressure?
The haemodynamic effects of glyceryl trinitrate are dependent on the rate and duration of delivery, with venous dilatation occurring at low levels of delivery and arterial effects seen more rapidly at higher rates.
Hargreaves et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: