Why the study?
Currently there is no drug therapy for abdominal aortic aneurysm (AAA).
Does telmisartan 40 mg reduce AAA growth in patients with small abdominal aortic aneurysms?
Population
210 patients with 35- to 49-mm AAAs recruited from Australia, the Netherlands, and the US
Comparison
Telmisartan, 40 mg vs identical placebo
Design
Randomized, double-blind, placebo-controlled trial
Authors
Loading...
Telmisartan did not slow small AAA growth; underpowered RCT leaves ARB efficacy open for larger trials.
Does telmisartan 40 mg reduce AAA growth in patients with small abdominal aortic aneurysms?
Telmisartan 40 mg daily did not significantly slow the growth of small abdominal aortic aneurysms compared to placebo, though the trial was underpowered.
Golledge et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: