Hypotensive Mechanisms of Antihypertensives Based on the Water Tank Model

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Population

Theoretical water tank model of body fluid volume-blood pressure regulation

Design

Other

Authors

Discussion

A theoretical water tank model can schematically illustrate the distinct hemodynamic mechanisms of various antihypertensive drug classes.

Population

Theoretical water tank model of body fluid volume-blood pressure regulation

Intervention

Antihypertensive drugs (vasodilators, beta-blockers, converting-enzyme inhibitors, diuretics)

Outcome

Hemodynamic changes (mean arterial pressure, cardiac output, total peripheral resistance, urinary Na+ excretion rate)

A theoretical water tank model can schematically illustrate the distinct hemodynamic mechanisms of various antihypertensive drug classes.

Kimura et al. (1989) studied this question.

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