Why the study?
Is c-kit activation necessary for bone marrow progenitor cell mobilization and prevention of heart failure after cardiac ischemic injury in mice?
Is c-kit activation necessary for bone marrow progenitor cell mobilization and prevention of heart failure after cardiac ischemic injury in mice?
The c-kit signaling pathway is essential for endogenous bone marrow progenitor cell mobilization and cardiac repair following myocardial infarction.
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Should not change post-MI care; leaves open whether c-kit activation improves human cardiac repair.
Fazel et al. (2007) studied this question.
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