Coupling micro‐LC and capillary GC as a powerful tool for the analysis of complex mixtures

A multidimensional chromatography system with a packed fused silica Micro‐LC column connected on‐line with capillary gas chromatography is presented. The Micro‐LC column is used for group separation. Whole peaks are injected into the capillary GC column via an on‐column injector. The reproducibility of the proposed transfer system for polyaromatic hydrocarbons is 3% to 7% relative standard deviation. The potential of this on‐line Micro‐LC‐GC system is demonstrated by the analyses of PAH's and of a complex light gasoline fraction.