Why the study?
Are ACE-ins/del and ATR1166A/C polymorphisms associated with adverse clinical outcomes in very-low-birthweight infants?
Are ACE-ins/del and ATR1166A/C polymorphisms associated with adverse clinical outcomes in very-low-birthweight infants?
Polymorphisms in the renin-angiotensin system (ACE-ins/del and ATR1166A/C) do not appear to be associated with adverse outcomes in very-low-birthweight infants.
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No association seen in this VLBW cohort; leaves open prognostic value of RAS polymorphisms and should not change practice.
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Spiegler et al. (2009) studied this question.
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