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April 1, 1992Molecular and Cellular BiologyOpen Access

The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes.

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Authors

MGMichael S. GermanUniversity of California, San FranciscoLML G MossBrigham Young UniversityJWJ WangUniversity of California, San Francisco

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German et al. (1992) studied this question.

synapsesocial.com/papers/6a90d9af504d7cdc493e7647https://doi.org/10.1128/mcb.12.4.1777
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene.1991 · 132 citations
  2. 2A cDNA from a mouse pancreatic β cell encoding a putative transcription factor of the insulin gene1990 · 90 citations
  3. 3Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei1983 · 11,637 citations
  4. 4IAPP/amylin gene transcriptional control region: evidence for negative regulation1990 · 25 citations
  5. 5Systematic Binding Analysis of the Insulin Gene Transcription Control Region: Insulin and Immunoglobulin Enhancers Utilize Similar Transactivators1988 · 99 citations