Population
Human plasma samples for a clinical pharmacokinetic study
Design
Other
Authors
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Enables simultaneous plasma quantification of these agents; leaves open clinical adoption pending real-world cardiovascular validation.
A highly sensitive and robust LC-MS/MS method was successfully developed and validated for the simultaneous measurement of simvastatin acid, amlodipine, and valsartan in human plasma.
Ramani et al. (2009) studied this question.
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