Why the study?
Do DOACs improve periprocedural safety and efficacy compared to warfarin in patients with nonvalvular atrial fibrillation?
Population
Patients with nonvalvular atrial fibrillation undergoing periprocedural management
Comparison
Direct oral anticoagulants as a class, managed… vs Warfarin, managed with either an interrupted or…
Design
Meta-analysis
Follow-up
30-day
Authors
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Supports comparable periprocedural safety of DOACs and warfarin in AF; leaves open optimal strategies for high-risk procedures.
Do DOACs improve periprocedural safety and efficacy compared to warfarin in patients with nonvalvular atrial fibrillation?
In patients with nonvalvular AF, periprocedural use of DOACs is as safe and effective as warfarin, and an uninterrupted DOAC strategy significantly reduces major bleeding compared to uninterrupted warfarin.
Nazha et al. (2018) studied this question.
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