Immunity to poliomyelitis develops rapidly with age and is more prevalent in urban compared to rural populations.
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Age- and setting-specific polio immunity patterns warrant surveillance consideration; leaves open relevance in vaccinated populations.
Immunity to poliomyelitis, as indicated by neutralization tests, has been shown to be widespread. A notion of the mechanism through which it comes about may be gained from a consideration of the rapidity with which it develops in reference to age and concentration of population. Infants born of immune mothers are immune to poliomyelitis for at least the early months of life: 1 The age distribution of the disease and neutralization tests show that this immunity is lost by the end of the first year. The age distribution further indicates an increasing immunity in the population with increasing age. Neutralization tests on persons of different ages have shown that nine tenths of urban persons become immune by the time adult life is reached. 2 The marked discrepancy between the amount of immunity to poliomyelitis in urban and in rural populations suggests that its extent and rapidity of development are related
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Stefan Krämer (1932) studied this question.
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