This preclinical study demonstrates that alpha-adrenoceptors in the rabbit left atrium mediate inotropic effects and prolong the functional refractory period, with secondary amines having a greater effect than primary amines.
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Preclinical rabbit data; leaves open alpha-adrenoceptor mediation of inotropy and refractoriness in human myocardium.
B. G. Benfey (1973) studied this question.
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