Why the study?
What is the prevalence of theoretical and actual adverse drug interactions in outpatients on long-term oral anticoagulants or adrenergic neuron-blocking drugs?
What is the prevalence of theoretical and actual adverse drug interactions in outpatients on long-term oral anticoagulants or adrenergic neuron-blocking drugs?
Theoretical drug interactions are common in patients on anticoagulants and adrenergic neuron-blockers, but actual adverse interactions occur much less frequently.
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Alerts based on theoretical interactions may overstate risk; leaves open whether real-world data can refine outpatient alert systems.
Starr et al. (1972) studied this question.
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