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May 2, 2004Acta Oto-Laryngologica

Laryngeal Paraganglioma: An Updated Critical Review

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Population

Patients with laryngeal paragangliomas (76 recognized cases reported in the world literature)

Design

Review

Authors

DMDavid MyssiorekMontefiore Health SystemARAlessandra RinaldoUniversity of UdineLBLeon BarnesNovartis (Switzerland)

Discussion

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Implication

May support surgical excision after IHC confirmation for laryngeal paragangliomas; leaves open need for prospective validation before changing practice.

Structured PICO

P
Population
Patients with laryngeal paragangliomas (76 recognized cases reported in the world literature)
I
Intervention
Evaluation (MRI, 111In pentetreotide scanning, immunohistochemical markers) and surgical excision (thyrotomy or laser excision)

Laryngeal paragangliomas are rare benign tumors that require precise immunohistochemical diagnosis to avoid misclassification as malignant neuroendocrine tumors and are best managed with surgical excision.

Cite This Study

Myssiorek et al. (2004) studied this question.

synapsesocial.com/papers/6a90ec99efab70d99b73d263https://doi.org/10.1080/00016480410017576
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Radiological Evaluation of Paragangliomas of the Head and Neck1979 · 35 citations
  2. 2Paraganglioma of the Inferior Laryngeal Paraganglia: A Case Report1992 · 23 citations
  3. 3Subglottic paraganglioma1997 · 26 citations
  4. 4Relapsing paraganglioma of the inferior laryngeal paraganglion: Case report and review of the literature2001 · 24 citations