Key result
Microlaryngoscopic excision successfully removed an accidentally diagnosed laryngeal paraganglioma, with definitive diagnosis achieved via histopathologic examination and immunohistochemistry.
Why the study?
Paragangliomas rarely involve the larynx and continue to represent a diagnostic challenge.
Case Report (n=1)
Microlaryngoscopic excision is an effective treatment for rare laryngeal paragangliomas, which require histopathologic examination for definitive diagnosis.
Supports microlaryngoscopic excision for rare laryngeal paraganglioma; leaves open need for larger series to guide management.
Paragangliomas are rare neuroendocrine tumors that uncommonly involve the larynx, and still represent a diagnostic challenge. Laryngeal paragangliomas are reported to derive from non-neuronal cells of the superior laryngeal nerve or of the recurrent laryngeal nerve, and are usually not functionally active; however, can become clinically evident causing airway obstruction, hoarseness and/or swallowing difficulty. A rare case of laryngeal paraganglioma of the aryepiglottic fold diagnosed accidentally, and then successfully removed surgically by microlaryngoscopic excision, is presented. Definitive diagnosis was only possible by histopathologic examination and immunohistochemistry; surgery is reported to be the treatment of choice for these tumors.
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Stomeo et al. (2021) conducted a case report in Laryngeal paraganglioma (n=1). Microlaryngoscopic excision was evaluated on Successful surgical removal and definitive diagnosis. Microlaryngoscopic excision successfully removed an accidentally diagnosed laryngeal paraganglioma, with definitive diagnosis achieved via histopathologic examination and immunohistochemistry.
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