Why the study?
Atrial fibrillation is common in patients with comorbidities, and the study aimed to assess 2-year clinical thromboembolic outcomes in a tertiary care center in India.
Despite high rates of oral anticoagulant prescription in AF patients, poor INR control leads to significant thromboembolic events, highlighting the need for frequent monitoring and adherence.
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Observational Indian AF cohort data on thromboembolic events; leaves open need for prospective validation before practice change.
BACKGROUND Fibrillation is a common arrhythmia especially in patients with valvular heart , hypertension, heart failure, and chronic obstructive lung disease. Aim of study is to assess the clinical outcomes of thromboembolic events such as , transient ischemic attack, myocardial infarction and peripheral embolism patients with atrial fibrillation on a 2 year follow up in a tertiary care center in . diagnosed with atrial fibrillation in both outpatient and inpatient were included. A total of 329 patients was included and followed up 2 years and analysed for outcomes. AF was diagnosed in 42.6 % (n = 140), persistent in 23.1 % (n = 76) paroxysmal in 34.7 % (n = 113). Valvular AF (moderate and severe mitral , prosthetic mechanical valve) was present in 26.7 % (n = 88) and AF in 73.3 % (n = 241). 74.8 % (n = 246) of AF patients were on oral and 4 were on NOAC. During 24 months of follow up, 26 patients (7.9 %) developed thromboembolic events. All were ischemic stroke and 4 were stroke. 4 of these patients defaulted anticoagulants. Time in therapeutic >60 % (good control) was present in only 3 out of the 26 patients. majority of the patients were on oral anticoagulants, they were not under control (subtherapeutic INR). Frequent monitoring with adequate and adherence to therapy can improve the outcomes in AF .
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Satheesan et al. (2020) studied this question.
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