Why the study?
Are plasma levels and cardiac release of atrial natriuretic factor increased in patients with cirrhosis and ascites compared to controls?
Population
35 patients with cirrhosis and ascites, 18 healthy volunteers, and 11 control patients admitted for thoracic…
Comparison
Measurement of plasma immunoreactive atrial… vs Healthy volunteers and control patients without…
Design
Cross-sectional
Authors
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May reflect compensatory volume regulation in cirrhosis; hypothesis-generating for mechanistic and therapeutic roles.
Are plasma levels and cardiac release of atrial natriuretic factor increased in patients with cirrhosis and ascites compared to controls?
Patients with cirrhosis and ascites have significantly elevated cardiac release and plasma levels of atrial natriuretic factor compared to controls.
Ginès et al. (1988) studied this question.