Why the study?
Does freeze-drying or deep-freezing bone allografts reduce their antigenicity in a rabbit model?
Population
New Zealand white rabbits (recipients) and Dutch belted rabbits (donors)
Comparison
Freeze-dried cortical and corticocancellous bone… vs Fresh allografts and deep-frozen…
Design
Preclinical
Authors
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No immediate clinical implications from rabbit data; leaves open human immunogenicity trials for processed allografts.
Does freeze-drying or deep-freezing bone allografts reduce their antigenicity in a rabbit model?
Freeze-dried cortical bone allografts are less antigenic than fresh or deep-frozen bone in a rabbit model.
Ge et al. (1976) studied this question.
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