Why the study?
Understanding environmental and genetic factors contributing to AF is important for determining management tactics and predicting disease course.
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Design
Overview of studies
Chromosome 10 SNPs may aid AF genetic risk research; leaves open clinical validation and utility.
Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF.
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Nikulinа et al. (2021) studied this question.
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