This editorial discusses the validation and physiological basis of calculating right ventricular ejection fraction from pressure curves during cardiac catheterisation in pulmonary hypertension.
In the present issue of the European Respiratory Journal , Heerdt et al. [1] report on the validation of right ventricularejection fraction (RVEF) calculated from a pressure curve at cardiac catheterisation. This is of great interest as right ventricular (RV) function is the main determinant of symptomatology and outcome in pulmonary hypertension [2], and RVEF accordingly adds significantly to risk stratification in these patients [3]. However, ejection fraction (EF) is a ratio of stroke volume (SV) to end-diastolic volume (EDV), with no pressure in the equation. So, how is it possible to calculate a volume ratio from pressure measurements? Right ventricular ejection fraction can be calculated from a pressure curve
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Naeije et al. (2020) studied this question.
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