Population
Patients with connective tissue diseases and animal models
Design
Review
Authors
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Does not support changing SLE management; leaves open whether chronic viral infection drives autoimmunity.
This review proposes the hypothesis that chronic viral infections play a key role in the pathogenesis of systemic lupus erythematosus and related connective tissue diseases.
Morris Ziff (1971) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: