August 25, 2017Pediatrics & NeonatologyOpen Access

The natural history of the patients with Duchenne muscular dystrophy in Taiwan: A medical center experience

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Population

39 patients diagnosed with Duchenne muscular dystrophy between 1999 and 2016 at Kaohsiung Medical University…

Design

Cohort

Follow-up

mean 6.76 years

Authors

WLWen‐Chen LiangKaohsiung Medical University CWChen‐Hua WangKaohsiung Medical University PCPo-Ching ChouCathay General Hospital

Discussion

Member takes

Implication

Supports similar DMD progression in Taiwanese patients; extends mutation spectrum data but remains hypothesis-generating for regional differences.

Structured PICO

Population

39 patients diagnosed with Duchenne muscular dystrophy (DMD) between 1999 and 2016 at Kaohsiung Medical University Hospital, Taiwan.

Outcome

Natural history and clinical phenotypes, including onset age of walking ability loss, respiratory insufficiency, cardiomyopathy, scoliosis, and genetic mutation profile.

The clinical course of DMD in Taiwan is consistent with other populations, though the proportion of point mutations or small deletions/insertions is higher, and cardiac ejection fraction may not be a reliable biomarker for early cardiac problems.

Cite This Study

Liang et al. (2017) studied this question.

synapsesocial.com/papers/6a910d7802b8c0248acaeab5 https://doi.org/10.1016/j.pedneo.2017.02.004

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Implication

Supports similar DMD progression in Taiwanese patients; extends mutation spectrum data but remains hypothesis-generating for regional differences.

The natural history of the patients with Duchenne muscular dystrophy in Taiwan: A medical center experience

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The natural history of the patients with Duchenne muscular dystrophy in Taiwan: A medical center experience

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider