Why the study?
What is the incidence of thyroid disease in patients with hypertrophic cardiomyopathy?
What is the incidence of thyroid disease in patients with hypertrophic cardiomyopathy?
There is an apparent association between thyroid disease and hypertrophic cardiomyopathy, with 13% of patients in this series having a history of thyroid abnormalities.
Should not change screening practices in hypertrophic cardiomyopathy; hypothesis-generating for a possible association requiring larger studies.
The investigative findings of patients considered to have possible hypertrophic cardiomyopathy were examined, and 31 of these fulfilling defined criteria for the disease were reviewed in detail, with emphasis on thyroid abnormalities. Four patients had a history of thyroid disease (13%). Explanations considered for the apparent association were the effects of hyperthyroidism on normal, or more probably, incipiently abnormal myocardium.
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Bell et al. (1978) studied this question.
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