In a patient with Brugada syndrome, spontaneous T wave alternans diminished while ST elevation increased following Na+ channel blockade, glucose loading, and atrial pacing.
Single Brugada case shows TWA-ST dissociation under provocation; leaves open any prognostic or management implications.
Spontaneous T wave alternans in Brugada syndrome. A 43-year-old man with an episode of syncope showed ECG patterns of coved-type ST elevation in leads V1-V3 and right bundle branch block pattern. The patient had spontaneous T wave alternans at baseline, and T wave alternans diminished with distinct development of ST elevation after administration of Na+ channel blocker, and during oral glucose load and atrial pacing. Na+ channel mutation may contribute to the genesis of his ECG changes.
No takes yet. Share an insight, caveat, or question.
Nishizaki et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: