ε-Sarcoglycan, a Broadly Expressed Homologue of the Gene Mutated in Limb-Girdle Muscular Dystrophy 2D
Population
Embryonic and adult muscle and nonmuscle cells
Comparison
Identification and characterization of… vs Alpha-delta sarcoglycans
Design
Preclinical
Authors
Discussion
Loading...
Member takes
Implication
Suggests sarcoglycan complexes may mediate membrane interactions beyond muscle; leaves open roles in non-muscle cells and cardiomyopathy.
Structured PICO
P
Population
Embryonic and adult muscle and nonmuscle cells
I
Intervention
Identification and characterization of epsilon-sarcoglycan
C
Comparator
Alpha-delta sarcoglycans
O
Outcome
Expression and distribution of epsilon-sarcoglycan
The identification of broadly expressed epsilon-sarcoglycan suggests that sarcoglycan-containing complexes may mediate membrane-matrix interactions in many cell types beyond striated muscle.
Cite This Study
Ettinger et al. (1997) studied this question.