The authors have built a small animal Positron Emission Tomograph (YAP-PET) based on four matrices of 400 YAP:Ce finger crystals (2/spl times/2/spl times/30 mm/sup 3/ each) coupled to a Position Sensitive PhotoMultiplier Hamamatsu R2486-06. The system consists of four detectors on a rotating gantry with a variable diameter from 10 and 25 cm. The read-out and data acquisition system are handled by NIM-CAMAC standard electronics. The tomograph has a total Field Of View (FOV) of 4/spl times/4/spl times/4 cm/sup 3/ that is appropriate for mice and rat studies. A spatial resolution /spl les/2 mm over 3/spl times/3/spl times/3 cm/sup 3/ FOV has been measured, with a peak sensitivity for a point source of about 614 cps//spl mu/Ci for a gantry diameter of 15 cm and an energy threshold of 50 keV.
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Domenico et al. (1998) studied this question.
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