Are diabetic hearts more resistant to ischemia/reperfusion injury?

Male rats with streptozotocin-induced diabetes (1-week and 4-week duration) and non-diabetic controls

Streptozotocin-induced diabetes (1-week and 4-week duration) subjected to 20 min of global ischemia and 30 min reperfusion in an isolated working heart model

Non-diabetic control rats subjected to the same ischemia/reperfusion protocol

Cardiac impairment measured by left ventricular developed pressure (LVDP), left ventricular end-diastolic pressure (LVEDP), maximum positive and negative dP/dt, and incidence of reperfusion-induced ventricular fibrillation (VF)surrogate