Why the study?
Does the timing of ventricular extrasystoles affect mitral valve closure and reflux?
Does the timing of ventricular extrasystoles affect mitral valve closure and reflux?
Ventricular extrasystoles, regardless of their timing in the cardiac cycle, generally cause minimal to no mitral reflux.
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Minimal mitral reflux occurs with ventricular extrasystoles irrespective of timing; leaves open relevance to arrhythmia management in mitral valve disease.
Vandenberg et al. (1969) studied this question.
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