The identification of a novel exon 1c-derived N terminus in Ca(V)1.2 channels of arterial myocytes reveals a mechanism for tissue-specific calcium signaling and regulation by auxiliary subunits.
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May influence arterial Ca(V)1.2 function in a splice-specific manner; leaves open any role in human vascular tone or therapy.
Cheng et al. (2007) studied this question.
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