Variations of Serum HDL Cholesterol Level During the Course of Acute Myocardial Infarction

Serum HDL cholesterol (HDL-C), total cholesterol (TC), Atherogenic Index (TC-HDL-C/HDL-C) and triglyceride (TG) were determined in the 57 patients during the course of acute myocardial infarction (AMI).Results:1) Serum HDL-C was decreased and Atherogenic Index was increased significantly during 24 hours after AMI, compared with the normal control.2) Serum TC and HDL-C decreased progressively in the first two week of AMI and therafter gradually increased, but not returned to the initial levels after two months. Atherogenic Index rose to maximum after two weeks and then dropped gradually. Serum TG showed no significant changes during the course of AMI.3) In the aged patients over 70 years, serum HDL-C was considered not to be negative coronary risk factor so as to younger patients under 59 years.4) The decrease of the serum HDL-C during the first week of AMI showed a positive correlation with the infarct size.