Why the study?
Does the ACE DD genotype increase breast cancer risk in Caucasian postmenopausal women compared to the II genotype?
Does the ACE DD genotype increase breast cancer risk in Caucasian postmenopausal women compared to the II genotype?
The ACE DD genotype is associated with an increased risk of breast cancer and reduced cancer-free survival in Caucasian postmenopausal women.
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ACE DD genotype may inform risk stratification in postmenopausal women; leaves open prospective validation before clinical adoption.
Ladd et al. (2005) studied this question.
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