Population
7 anaesthetized dogs
Comparison
Variations in mean arterial blood pressure (MAP) vs MAP 81-100 mmHg (control) vs MAP 61-80 mmHg
Design
Preclinical
Authors
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MAP <80 mmHg may reduce medullary pressure in dogs; leaves open human clinical relevance and translation.
In anaesthetized dogs, long bone medullary pressures remain constant at mean arterial pressures above 80 mmHg but decrease significantly below this threshold.
Tøndevold et al. (1979) studied this question.
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