Arthralgia and Rubella Immunization

Letters and Corrections1 January 1978Arthralgia and Rubella ImmunizationSTEPHEN J. LERMAN, M.D., MARCIA R. SILVER, M.D., GEORGE A. NANKERVIS, PH.D., M.D.STEPHEN J. LERMAN, M.D.Search for more papers by this author, MARCIA R. SILVER, M.D.Search for more papers by this author, GEORGE A. NANKERVIS, PH.D., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-88-1-131_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In a paper on our 1969 clinical trial of HPV-77:DE-5 live attenuated rubella virus vaccine in adolescent girls and young women (1), we described in detail a 17-year-old vaccinee (subject #281) who developed moderate arthralgia of her knees and hips, moderate-to-severe arthritis of her fingers, and a painful ganglion. We noted that intermittent arthralgia of her knees and hips had persisted for a year after vaccination. We report here an 8-year follow-up.Subject #281 is now a 25-year-old resident in internal medicine. At 2-to-3-month intervals and in association with the onset of cool, damp weather, she experiences...References1. LERMAN S, NANKERVIS G, HEGGIE A, and GOLD E: Immunologic response, virus excretion, and joint reactions with rubella vaccine. A study of adolescent girls and young women given live attenuated virus vaccine (HPV-77:DE-5). Ann Intern Med 74:67-73, 1971 LinkGoogle Scholar2. KANTOR T and TANNER M: Rubella arthritis and rheumatoid arthritis. Arthritis Rheum 5:378-383, 1962 CrossrefMedlineGoogle Scholar3. SPRUANCE S, KLOCK L, and BAILEY A: Recurrent joint symptoms in children vaccinated with HPV-77:DK-12 rubella vaccine. J Pediatr 80:413-417, 1972 CrossrefMedlineGoogle Scholar4. THOMPSON G, WEISS J, and ELOISE M: Intermittent arthritis following rubella vaccination. A three-year follow-up. Am J Dis Child 125:526-530, 1973 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: STEPHEN J. LERMAN, M.D.; MARCIA R. SILVER, M.D.; GEORGE A. NANKERVIS, PH.D., M.D.Affiliations: Pediatric Infectious Disease Unit University of Nebraska Medical Center Omaha, NE 68105 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 January 1978Volume 88, Issue 1Page: 131-131KeywordsAdolescentsArthralgiaArthritisClinical trialsDeoxyadenosine monophosphateHipKneesRubellaVaccines ePublished: 1 December 2008 Issue Published: 1 January 1978 PDF downloadLoading ...