Probabilities of Pituitary-Adrenal Responsiveness After Steroid Therapy

Article1 July 1964Probabilities of Pituitary-Adrenal Responsiveness After Steroid TherapyT. S. DANOWSKI, M.D., JAMES V. BONESSI, M.D., GEORGE SABEH, M.D., ROGER D. SUTTON, M.D., MARSHALL W. WEBSTER JR., MARGARET E. SARVER, M.D.T. S. DANOWSKI, M.D.Search for more papers by this author, JAMES V. BONESSI, M.D.Search for more papers by this author, GEORGE SABEH, M.D.Search for more papers by this author, ROGER D. SUTTON, M.D.Search for more papers by this author, MARSHALL W. WEBSTER JR.Search for more papers by this author, MARGARET E. SARVER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-61-1-11 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptData accumulated in this laboratory provide a basis for some generalizations concerning pituitary-adrenal responsiveness in subjects who had received adrenal steroids or adrenocorticotrophic hormone (ACTH) in small or large dosages for brief or for prolonged periods and in spontaneous Cushing's syndrome in remission after removal of an adrenal adenoma.MATERIALS AND METHODSGROUP AGroup A was made up of 117 females, 9.5 to 52 years of age, who received hydrocortisone-type steroids in replacement-displacement (that is, small) dosages in treatment of amenorrhea, hirsutism, acne, or infertility, and combinations thereof (Table 1). In most of these, the pretherapy urinary 17-ketosteroids (1)...References1. 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Sabeh and Sarver are Clinical Fellows at the University of Pittsburgh School of Medicine. Dr. Bonessi is a Former Clinical Fellow at the University of Pittsburgh School of Medicine.Requests for reprints should be addressed to T. S. Danowski, M.D., 930-936 Health Professions Bldg., University of Pittsburgh School of Medicine, Pittsburgh 13, Pennsylvania. 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Hypophyseo-adrenocortical inhibition.INTERMITTENT THERAPY WITH CORTICOTROPHINIatrogenic ACTH-Cortisol Insufficiency. I. Duration of InsufficiencyHydrocortisone and/or desiccated thyroid in physiologic dosageAdrenocortical Function During Intermittent Corticosteroid TherapyDONALD A. ADAMS, M.D., ERNEST M. GOLD, M.D., HARVEY C. GONICK, M.D., F.A.C.P., MORTON H. MAXWELL, M.D., F.A.C.P.Inhibitors of adrenal cortical functionMedical Treatment of Ulcerative ColitisHereditary Addison's Disease in Relation to Diabetes MellitusClinical Assessment of the Peroral Metopirone TestWirkung von ACTH auf die Restitutionsphase der Nebennierenrinde nach langfristiger CortisongabeDie intravenöse Glucosebelastung und die Erfassung einer latenten Nebennierenrindeninsuffizienz während und nach Corticosteroidtherapie 1 July 1964Volume 61, Issue 1Page: 11-26KeywordsAcneAdrenocorticotropic hormoneEndocrinologyHeartHospital medicineInfertilityIngestionMedical educationResearch laboratoriesSteroid therapy Issue Published: 1 July 1964 PDF DownloadLoading ...