Why the study?
Does tolerance to intravenous flecainide or propafenone predict the safety of oral pill-in-the-pocket treatment in patients with recent-onset atrial fibrillation?
Does tolerance to intravenous flecainide or propafenone predict the safety of oral pill-in-the-pocket treatment in patients with recent-onset atrial fibrillation?
Tolerance to intravenous flecainide or propafenone does not predict the safety of oral pill-in-the-pocket treatment for recent-onset atrial fibrillation, highlighting the necessity of in-hospital testing of the oral dose.
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IV tolerance does not predict oral pill-in-the-pocket safety; leaves open whether supervised oral testing is required before outpatient use in recent-onset AF.
Alboni et al. (2010) studied this question.
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