Why the study?
Does arterial counterpulsation limit ischemia and necrosis in patients with myocardial infarction?
Does arterial counterpulsation limit ischemia and necrosis in patients with myocardial infarction?
Arterial counterpulsation is considered a physiologically sound approach to limit ischemia and necrosis in acute myocardial infarction, particularly in cardiogenic shock.
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Physiological rationale supports counterpulsation in AMI shock; leaves open confirmation of clinical benefit in randomized trials.
Arterial counterpulsation is a major advance in the treatment of myocardial ischaemia in association with myocardial infarction. Counterpulsation is based on sound physiological principles and can be expected to limit ischaemia and necrosis when applied within the first 12 to 24 hours of infarction. It has been used in massive infarction with cardiogenic shock, and in threatening infarction. Good results at both ends of a clinical spectrum suggest an important role throughout the spectrum. Studies in progress are attempting to define this role.
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Michael F. O’Rourke (1977) studied this question.
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