Key result
Arterial counterpulsation in severe refractory heart failure complicating MI yielded hospital survival rates of 34% in patients with shock and 65% in those without shock.
Why the study?
Does arterial counterpulsation improve survival in patients with severe refractory heart failure complicating acute myocardial infarction?
Observational (n=100)
Does arterial counterpulsation improve survival in patients with severe refractory heart failure complicating acute myocardial infarction?
Arterial counterpulsation may improve short- and long-term survival in patients with severe refractory heart failure and shock complicating acute myocardial infarction when initiated promptly.
Answers are grounded in this paper and cite their sources.
Suggests possible survival benefit from prompt arterial counterpulsation in refractory post-MI shock; hypothesis-generating and requires randomized confirmation.
The role of arterial counterpulsation was sought in 100 patients with severe refractory cardiac failure complicating myocardial infarction. Seventy-four were in shock and 26 were not. Average duration of counterpulsation was 7.0 days. Hospital survival was 34 per cent (25/74) in shock (predicted less than 10%) and 65 per cent in patients who were not in shock (predicted less than 50%). Survival at 4 years was 10 +/- 4 per cent in shock and 37 +/- 11 per cent in patients not in shock; functional status was class 1 or 2 in 5 of 9 patients in shock and in 8 of 12 survivors not in shock. Results were best when counterpulsation was started early after onset of symptoms, when ischaemic pain was still present, or when a mechanical defect was corrected surgically. Early coronary artery bypass surgery performed alone in 9 patients did not influence survival or functional status. Complications of counterpulsation occurred in 17 patients in shock and in 2 patients not in shock, all but 6 on the first day; none directly caused death. Counterpulsation is an effective and safe adjunct to medical treatment of complicated infarction provided the intervention is prompt.
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O’Rourke et al. (1979) conducted an observational in severe refractory cardiac failure complicating acute myocardial infarction (n=100). Arterial counterpulsation was evaluated on Hospital survival. Arterial counterpulsation in severe refractory heart failure complicating MI yielded hospital survival rates of 34% in patients with shock and 65% in those without shock.
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