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May 1, 1993Journal of Hypertension

Circadian blood pressure variation in diabetic patients with autonomic neuropathy

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Why the study?

Does ambulatory blood pressure monitoring detect abnormal circadian blood pressure variations in diabetic patients with autonomic neuropathy compared to non-diabetic controls?

Population

53 outpatients, comprising 38 normotensive diabetics and 15 age- and sex-matched non-diabetic controls at…

Comparison

Ambulatory blood pressure monitoring (ABPM) vs 15 age- and sex-matched non-diabetic controls

Design

Case-control

Authors

TITetsurou IkedaAomori UniversityTMTatsuaki MatsubaraAichi Mizuho CollegeYSYuzo SatoKaken Pharmaceutical (Japan)

Discussion

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Implication

ABPM may flag autonomic neuropathy effects on BP in diabetics; leaves open adjusted thresholds or risk models for prospective validation.

Structured PICO

Does ambulatory blood pressure monitoring detect abnormal circadian blood pressure variations in diabetic patients with autonomic neuropathy compared to non-diabetic controls?

P
Population
53 outpatients, comprising 38 normotensive diabetics and 15 age- and sex-matched non-diabetic controls at Nagoya University Hospital.
I
Intervention
Ambulatory blood pressure monitoring (ABPM)
C
Comparator
15 age- and sex-matched non-diabetic controls
O
Outcome
Circadian variations and indices of blood pressure variability (diurnal-nocturnal differences)surrogate

Ambulatory blood pressure monitoring reveals blunted circadian blood pressure variations in diabetic patients, which correlates with the severity of autonomic neuropathy.

Cite This Study

Ikeda et al. (1993) studied this question.

synapsesocial.com/papers/6a913e68be68d22e6965e7cahttps://doi.org/10.1097/00004872-199305000-00015
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Day and night variation in ambulatory blood pressure in type 1 diabetes mellitus with nephropathy and autonomic neuropathy1993 · 39 citations
  2. 2Ambulatory Blood Pressure and Heart Rate in Diabetic Patients: an Assessment of Autonomic Function1989 · 72 citations
  3. 3Loss of Nocturnal Decline in Blood Pressure in Diabetic Patients with Autonomic Neuropathy.1992 · 3 citations
  4. 4Diurnal blood pressure and blood pressure variability in diabetic normotensive and hypertensive subjects1992 · 43 citations
  5. 5Relationship between the progression of diabetic polyneuropathy and impaired circadian blood pressure variability2024 · 4 citations