Why the study?
Does central venous pressure accurately reflect pulmonary artery wedge pressure in patients undergoing elective infrarenal aortic surgery?
Does central venous pressure accurately reflect pulmonary artery wedge pressure in patients undergoing elective infrarenal aortic surgery?
Central venous pressure is an insensitive indicator of left ventricular filling pressure during elective infrarenal aortic surgery, supporting the recommendation for PAWP monitoring.
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CVP may inadequately reflect left ventricular filling pressure changes in aortic surgery; leaves open whether PAWP monitoring improves outcomes.
We designed a prospective study to determine whether cardiac ejection fraction as measured noninvasively could isolate a subset undergoing aortic surgery for whom central venous pressure (CVP) predicted pulmonary artery wedge pressure (PAWP). Sixteen patients were studied. Simultaneous values of PAWP and CVP were analyzed, using linear regression analysis. A significant correlation between CVP and PAWP was found for the entire patient population and for each of four time periods: preoperative, before and after aortic cross-clamping, during aortic cross-clamping, and postoperative. A significant correlation between PAWP and CVP was found during the entire perioperative period for 14 of the 16 patients. However, the slope of the regression line, or the sensitivity of the CVP in reflecting changes in PAWP, was greater than 0.5 in only seven of the 16 patients. There was no correlation between the preoperative ejection fraction and the CVP/PAWP. We conclude that the CVP is an insensitive indicator of left ventricular filling pressure in most patients accepted for elective infrarenal aortic surgery, and monitoring of the PAWP is recommended.
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Gary G. Nicholas (1983) studied this question.
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